Capillaries and arterioles are electrically coupled in hamster cheek pouch
نویسندگان
چکیده
منابع مشابه
Capillaries and arterioles are electrically coupled in hamster cheek pouch.
In this report we demonstrate electrical communication in the microcirculation between arterioles and capillary networks in situ. Microvessel networks in the hamster cheek pouch, which included capillaries and their feeding arterioles, were labeled with the voltage-sensitive dye di-8-ANEPPS by intraluminal perfusion through a micropipette. Pulses of 140 mM potassium solution were applied by pre...
متن کاملThe oxygen sensitivity of hamster cheek pouch arterioles. In vitro and in situ studies.
We tested the hypothesis that a parenchymally derived mediator is required for arterioles to exhibit oxygen sensitivity. To that end, the parenchyma was dissected and removed from around hamster cheek pouch arterioles, and the oxygen sensitivity of these "aparenchymal arteriolar segments" was studied, either in vitro, after cannulation, or in situ. Arteriolar segments in situ with and without p...
متن کاملCarcinogenesis in the Hamster Cheek Pouch
Pouches from three experimental and one control animal were excised for analysis at various times during the first week and thereafter each week of carcinogen application (9,10-dimethyl-l ,~-benzanthracene) until the 131h week, at which time large tumors were present in all remaining aninmls. IIistologic progression from normal through inflanmmtion, uniform hyperplasia, localized premalignant h...
متن کاملRole of EDHF in conduction of vasodilation along hamster cheek pouch arterioles in vivo.
We tested whether local and conducted responses to ACh depend on factors released from endothelial cells (EC) in cheek pouch arterioles of anesthetized hamsters. ACh was delivered from a micropipette (1 s, 500 nA), while arteriolar diameter (rest, approximately 40 microm) was monitored at the site of application (local) and at 520 and 1,040 microm upstream (conducted). Under control conditions,...
متن کاملResolution of smooth muscle and endothelial pathways for conduction along hamster cheek pouch arterioles.
In the cheek pouch of anesthetized male hamsters, microiontophoresis of Ach (endothelium-dependent vasodilator) or phenylephrine (PE; smooth muscle-specific vasoconstrictor) onto an arteriole (resting diameter, 30-40 microm) evokes vasodilation or vasoconstriction (amplitude, 15-25 microm), respectively, that conducts along the arteriolar wall. In previous studies of conduction, endothelial and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Physiology-Heart and Circulatory Physiology
سال: 1998
ISSN: 0363-6135,1522-1539
DOI: 10.1152/ajpheart.1998.275.4.h1489